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Politely – you are confusing "bioavailability" and "systemic dose" which is the only meaningful pharmacological aspect of drug efficacy. Dilutions matter. Concentrations matter. No need to contact one another. The CBD industry will be regulated by the FDA within the next year or so, which is when non-clinical trial claims (not just research papers) such as "water soluble is better" will go away. Good luck, be well, stay safe.
A case where a little knowledge can be dangerous. Sorry to debase your notions, but "water soluble" merely means "took a water repelling molecule and covered it with other chemicals that are attracted to water" (emulsified it). It's the SAME CBD MOLECULE. And will be metabolized the SAME way, whether presented in water or oil base. ANY ingested materials undergo "first pass metabolism" and ALL drugs lose ~80% – which is exactly why they're dosed at certain levels! And please don't "mix your CBD in a smoothie or coffee" – that simply dilutes the drug concentration. You're also misunderstanding drug delivery methods (sublingual which bypasses first metabolism vs ingested). Saying "water soluble is better" simply isn't scientifically or medically accurate. That's why there's no rush to make supplements like Fish OIL a water soluble, or vitamins A, D, E, and K water soluble. That's why the food industry stays with olive oil, or avacado oil – no rush to make these emulsified . . . oh, wait, yes we do, in salad dressings! We agree with one thing though, when the CBD industry is FDA regulated, and it will be, then claims like "water soluble CBD is better" will have to be clinically proven or they won't be permitted. Which is exactly why you don't hear about "water soluble drugs" from the existing supplement or drug industry – because they know it's poppycock and they aren't allowed to say such things. Ask yourself, "why am I only hearing about water soluble in the CBD industry (it's unregulated) and why mainly from this company (they're trying to get you to buy their product)?"
I tried the cbd oil. Did not like the taste. Been using the water soluble cbd and ove it. Take 5 mg add to a shot glass of water. I would recommend this to anyone. What do you think is the best one on the market? Tks
How do you convert the lipids (oil) from the plant's cbd resin to be water soluble? That's like making peanut oil water soluble… 🤔 If you're saying that making the oil into an emulsion makes it water soluble… That's the recipe for italian dressing.
You did a great job of getting the message out. More people need to see this, as most are taught oil is better as I did! I will order your water based now, bet the difference is amazing! Will come back on here and let others know of my comparison. Thanks for being out there. Namaste
Which would be better in skincare
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Politely – you are confusing "bioavailability" and "systemic dose" which is the only meaningful pharmacological aspect of drug efficacy. Dilutions matter. Concentrations matter. No need to contact one another. The CBD industry will be regulated by the FDA within the next year or so, which is when non-clinical trial claims (not just research papers) such as "water soluble is better" will go away. Good luck, be well, stay safe.
A case where a little knowledge can be dangerous. Sorry to debase your notions, but "water soluble" merely means "took a water repelling molecule and covered it with other chemicals that are attracted to water" (emulsified it). It's the SAME CBD MOLECULE. And will be metabolized the SAME way, whether presented in water or oil base. ANY ingested materials undergo "first pass metabolism" and ALL drugs lose ~80% – which is exactly why they're dosed at certain levels! And please don't "mix your CBD in a smoothie or coffee" – that simply dilutes the drug concentration. You're also misunderstanding drug delivery methods (sublingual which bypasses first metabolism vs ingested). Saying "water soluble is better" simply isn't scientifically or medically accurate. That's why there's no rush to make supplements like Fish OIL a water soluble, or vitamins A, D, E, and K water soluble. That's why the food industry stays with olive oil, or avacado oil – no rush to make these emulsified . . . oh, wait, yes we do, in salad dressings! We agree with one thing though, when the CBD industry is FDA regulated, and it will be, then claims like "water soluble CBD is better" will have to be clinically proven or they won't be permitted. Which is exactly why you don't hear about "water soluble drugs" from the existing supplement or drug industry – because they know it's poppycock and they aren't allowed to say such things. Ask yourself, "why am I only hearing about water soluble in the CBD industry (it's unregulated) and why mainly from this company (they're trying to get you to buy their product)?"
I tried the cbd oil. Did not like the taste. Been using the water soluble cbd and ove it. Take 5 mg add to a shot glass of water. I would recommend this to anyone. What do you think is the best one on the market? Tks
How do you convert the lipids (oil) from the plant's cbd resin to be water soluble? That's like making peanut oil water soluble… 🤔
If you're saying that making the oil into an emulsion makes it water soluble… That's the recipe for italian dressing.
You did a great job of getting the message out. More people need to see this, as most are taught oil is better as I did! I will order your water based now, bet the difference is amazing! Will come back on here and let others know of my comparison. Thanks for being out there. Namaste
Very informative. You are very handsome.