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  1. We tried CBD for our senior dog's joint pain/arthritis, but it didn't help. I really wanted it to work because I felt it was a more natural option. We did notice improved mobility and comfort when she was on carprofen. Our vet warned us that Carprofen wasn't good for her Liver in the long-term, but she was an old dog anyways (nearing end of life), and we just wanted her comfortable at that point.

  2. CBD is found to inhibit endocannabinoid signaling in a dose-dependent manner, likely by binding to CB1Rs' allosteric site and altering the potency of other primary ligands (e.g., endocannabinoids, THC)

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